Found 304 matching trials
Study to Evaluate Efficacy, Safety, Tolerability, and Pharmacodynamics of Entospletinib in Adults With Relapsed or Refractory Hematologic Malignancies PHASE2 The primary objective of the study is to evaluate efficacy of entospletinib...
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University of Alabama at Birmingham
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Taselisib and Enzalutamide in Treating Patients With Androgen Receptor Positive Triple-Negative Metastatic Breast Cancer PHASE1 This partially randomized phase Ib/II trial studies the side effects and be...
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University of Alabama, Birmingham
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Combination of Ibrutinib and As2O3 in the Treatment of CLL PHASE3 The purpose of this study is to determine whether the combination of As2O3 ...
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Multiple Locations
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PI3K Inhibitor BKM120 and Docetaxel in Treating Patients With Advanced Solid Tumor That is Locally Advanced, Cannot Be Removed By Surgery, or Metastatic PHASE1 This phase I trial studies the side effects and best dose of PI3K inhibitor...
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Roswell Park Cancer Institute
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NeoPHOEBE: Neoadjuvant Trastuzumab + BKM120 in Combination With Weekly Paclitaxel in HER2-positive Primary Breast Cancer PHASE2 This randomized, parallel cohort, two stage, double-blind, placebo-controll...
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Novartis Investigative Site
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Copanlisib With Ibrutinib for Patients With Recurrent/ Refractory Primary Central Nervous System Lymphoma (PCNSL) PHASE1 The purpose of this study is to test the safety of combined use of the stud...
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Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
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Clinical Study of HEC68498 in Patients With Advanced Refractory Solid Tumors PHASE1 Clinical study of HEC68498 in patients with advanced refractory solid tumor...
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The Fifth Medical Center of PLA Ceneral Hospital
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Safety and Efficacy Study of Tenalisib (RP6530) in Combination With Pembrolizumab in Relapsed or Refractory cHL PHASE1 To characterize safety, tolerability and to establish the maximum tolerated...
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University of Chicago
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PI3Kδ Inhibitor Parsaclisib Combined With Chidamide for the Treatment of Relapsed/Refractory Peripheral T-cell Lymphoma PHASE1 This is a prospective single-arm, multicenter, phase Ib clinical trial of P...
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Henan Cancer Hospital/The affiliated Cancer Hospital of ZhengZhou university
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A Phase II Study of Linperlisib (YY-20394) in Patients With Relapsed or Refractory Peripheral T/NK Cell Lymphoma PHASE2 This is a Phase II, single-arm study to evaluate the efficacy, safety, and ...
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MD Anderson Cancer Center
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